SEROTONERGIC SYSTEMS

Since its identification in neurons of the central nervous systems (CN S), serotonin (5-HT) has been implicated in the pathophysiology of psy chiatric disorders, such as schizophrenia, depression, generalized anx iety disorder (GAD), panic disorder (PD), and obsessive-compulsive dis order (OCD). These findings have stimulated research on brain 5-HT pat hways, especially during the last two decades as more selective drugs have been introduced into medical practice. This article reviews selec ted topics relevant for psychiatry.