Women with diabetes in pregnancy can be divided into two groups: women
with diabetes diagnosed before pregnancy (pregestational diabetes) an
d women with glucose intolerance diagnosed during pregnancy (gestation
al diabetes mellitus). The majority of women with pregestational diabe
tes have insulin-dependent diabetes mellitus (IDDM), but may also incl
ude early-onset non-insulin dependent diabetes mellitus (NIDDM). Gesta
tional diabetes mellitus (GDM) can represent first recognition of IDDM
or NIDDM. The expression of each of the forms of diabetes as a clinic
al disorder represents a complex interaction of genetic and environmen
tal factors. The prevalence of GDM varies between 0.15 and 4% and the
prevalence of pre-GDM 0.2-0.4% in European countries [1]. (C) 1997 Els
evier Science Ireland Ltd.