CAPILLARY GAS-CHROMATOGRAPHIC SEPARATION OF C-10-C-12 SECONDARY PHENYLALKANES ON MODIFIED CYCLODEXTRIN STATIONARY PHASES

The separation of isomers and enantiomers of branched C-10-C-12 phenyl alkanes by gas chromatography on fused silica capillary columns coated with some modified beta- and gamma-cyclodestrins was studied, It was shown that the separation of positional isomers of C-10-C-12 phenylalk anes on modified cyclodextrin capillary columns is not better than tha t on a column coated with modified polyethylene glycol, Differences we re found in the enantioselectivity of modified beta- and gamma-cyclode xtrins for the separation of C-10-C-12 secondary phenylalkane enantiom ers, While alkyl derivatives of beta-CDs resolve enantiomers of 3-phen ylalkanes, alkyl derivatives of gamma-CDs resolve enantiomers of 2-phe nylalkanes. Since shape selectivity factors of modified cyclodextrins have indicated no inclusion of the considered solutes in cyclodextrin cavities, enantioselective interactions most probably occur on the out er sphere of cyclodextrins.