S. Kumar et al., SEASONAL CYCLOTHYMIA TO SEASONAL BIPOLAR AFFECTIVE-DISORDER - A DOUBLE SWITCH AFTER STROKE, Journal of Neurology, Neurosurgery and Psychiatry, 63(6), 1997, pp. 796-797
The appearance of bipolar affective disorder after stroke depends on t
he presence of two factors: a predisposing factor of either genetic lo
ading or subcortical atrophy, and a lesion of specific corticolimbic p
athways involving the right hemisphere. Whether cyclothymia and season
al affective disorder further predispose to poststroke affective disor
der is not clear. A case is described which highlights these issues. T
he aetiological factors, pathophysiology, and diagnosis are discussed.