SIMPLE AND HIGH-YIELD SYNTHESIS OF (+ -)10,10'-DIMETHYL-DOTRIACONTAN-1,1'-DIOL AS A BUILDING-BLOCK FOR BRANCHED BOLA COMPOUNDS - PREPARATION OF OTRIACONTA-1,1'-DIYL-BIS[2-(TRIMETHYLAMMONIO)ETHYL PHOSPHATE] ANDTHE CORRESPONDING UNBRANCHED EQUIVALENT/

Authors
HEISER UF WOLF R DOBNER B
Citation
Uf. Heiser et al., SIMPLE AND HIGH-YIELD SYNTHESIS OF (+ -)10,10'-DIMETHYL-DOTRIACONTAN-1,1'-DIOL AS A BUILDING-BLOCK FOR BRANCHED BOLA COMPOUNDS - PREPARATION OF OTRIACONTA-1,1'-DIYL-BIS[2-(TRIMETHYLAMMONIO)ETHYL PHOSPHATE] ANDTHE CORRESPONDING UNBRANCHED EQUIVALENT/, Chemistry and physics of lipids, 90(1-2), 1997, pp. 25-30
Citations number
13
Categorie Soggetti
Biology,Biophysics
Journal title
Chemistry and physics of lipids → ACNP
ISSN journal
00093084
Volume
90
Issue
1-2
Year of publication
1997
Pages
25 - 30
Database
ISI
SICI code
0009-3084(1997)90:1-2<25:SAHSO(>2.0.ZU;2-#
Abstract
The synthesis of a specially methyl branched bipolar hydrocarbon chain is described by alkylation of 1,12-dibro-mododecane with two equivale nts of the dianion of undec-10-enoic acid. The subsequent transformati on includes the reduction of the carboxyl groups to methyl branches an d the hydroboration of the terminal olefines. The resulting 1,32 diol is suitable for phosphorylation in order to form the corresponding 1,1 'bis-phosphocholine. (C) 1997 Elsevier Science Ireland Ltd.