QUANTITATIVE NEAR-INFRARED SPECTROMETRY U SED FOR THE DETERMINATION OF THE CONTENT OF SENNOSIDES IN A PHYTOGENIC MATRIX

Authors
MOLT K ZEYEN F PODPETSCHNIGFOPP E
Citation
K. Molt et al., QUANTITATIVE NEAR-INFRARED SPECTROMETRY U SED FOR THE DETERMINATION OF THE CONTENT OF SENNOSIDES IN A PHYTOGENIC MATRIX, Die Pharmazie, 52(12), 1997, pp. 931-937
Citations number
6
Categorie Soggetti
Pharmacology & Pharmacy","Chemistry Medicinal
Journal title
Die Pharmazie → ACNP
ISSN journal
00317144
Volume
52
Issue
12
Year of publication
1997
Pages
931 - 937
Database
ISI
SICI code
0031-7144(1997)52:12<931:QNSUSF>2.0.ZU;2-W
Abstract
The sennoside content of a drug gained from Senna plants can be determ ined directly by NIR-spectrometry by measuring the original products i n diffuse reflection without further sample preparation. This however requires a previous calibration with standards the concentrations of w hich have to be determined by an adequate reference method. We show th at HPLC is suitable for this purpose.