TRANS-ADENOSINE 3',5'-CYCLIC N,N-DIMETHYLPHOSPHORAMIDATE ETHER SOLVATE, A CYCLIC-NUCLEOTIDE WITH AN EQUATORIAL DIMETHYLAMINO GROUP ON PHOSPHORUS

Authors
BOTTKA S TOMASZ J CRUSE WBT ZHANG S KENNARD O
Citation
S. Bottka et al., TRANS-ADENOSINE 3',5'-CYCLIC N,N-DIMETHYLPHOSPHORAMIDATE ETHER SOLVATE, A CYCLIC-NUCLEOTIDE WITH AN EQUATORIAL DIMETHYLAMINO GROUP ON PHOSPHORUS, Nucleosides & nucleotides, 16(12), 1997, pp. 2123-2131
Citations number
22
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
16
Issue
12
Year of publication
1997
Pages
2123 - 2131
Database
ISI
SICI code
0732-8311(1997)16:12<2123:T3NES>2.0.ZU;2-E
Abstract
trans-Adenosine 3',5'-cyclic N,N-dimethylphosphoramidate ether solvate crystallizes as monoclinic prisms elongated about the b-axis. The dio xaphosphorinane ring adopts a flattened chair conformation with an alm ost planar dimethylamino substituent equatorial. The purine ring confo rmation is anti. The ribose ring exists in a T-3(4) conformation.