SYNTHESIS OF THE OPTICALLY-ACTIVE CARBOCYCLIC ANALOGS OF THE 4 2'-DEOXYRIBONUCLEOSIDE MONOPHOSPHATES

Authors
SCHMITT L CAPERELLI CA
Citation
L. Schmitt et Ca. Caperelli, SYNTHESIS OF THE OPTICALLY-ACTIVE CARBOCYCLIC ANALOGS OF THE 4 2'-DEOXYRIBONUCLEOSIDE MONOPHOSPHATES, Nucleosides & nucleotides, 16(12), 1997, pp. 2165-2192
Citations number
23
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
16
Issue
12
Year of publication
1997
Pages
2165 - 2192
Database
ISI
SICI code
0732-8311(1997)16:12<2165:SOTOCA>2.0.ZU;2-P
Abstract
The (+)-enantiomer of the carbocyclic analogs of the four 2'-deoxyribo nucleoside monophosphate constituents of DNA, C-dAMP(2)(1: A), C-dGMP (1: G), C-dCMP (1: C), and C-TMP (1: T) have been synthesized via the Mitsunobu coupling reaction. Two new N-3-protected thymines were devel oped en route.