PROTEIN SPLICING - OCCURRENCE, MECHANISMS AND RELATED PHENOMENA

An increasing number of proteins are thought to self-splice post-trans lationally on the level of the polypeptide, producing two separate pro teins from one gene, neither of which is the protein predicted from th e gene sequence. The recent elucidation of the mechanism of splicing h as led to the identification of a number of post-translational protein modifications that use similar chemical pathways.