IRRADIATION METHODS FOR PRODUCTION OF HIGH SPECIFIC ACTIVITY RADIONUCLIDES IN NO CARRIER ADDED FORM

High Specific Activity Radio-Nuclides (HSARN) are a powerful tool to l abel-a large range of chemical species at very low concentration level s. In order to obtain these radiotracers in a very high specific activ ity form, it is necessary to optimize the production methods, to separ ate and purify them from the irradiated target without the addition of inactive carrier, to carry out a series of analytical and radioanalyt ical tests to determine their ''true'' specific activity and to verify a series of purity parameters. A review of irradiation methods and nu clear parameters adopted in our laboratories for the preparation of so me tens of radiotracers are presented.