The purpose of this study was to investigate the fire risk of laser re
surfacing in the presence of supplemental oxygen. This study aims at d
efining safety parameters of variables such as laser energy level, oxy
gen flow rate, and ''oxygen to laser target distance'' when oxygen is
delivered through a nasal cannula or nasopharyngeal tube. The typical
operating room environment was simulated in the laboratory using the Y
ucatan minipig animal model. The energy source was a Coherent Ultrapul
se CO2 laser. It was found that combustion did not occur at laser sett
ings of 500 mJ, 50 W, 100 kHz, and a density of 5, used in conjunction
with an oxygen flow rate of 6 liter/minute with the target area as cl
ose as 0.5 cm to the oxygen delivery. A total of 400 computer pattern
generator treatments were delivered using this energy setting without
observation of any combustion (p < 0.001). This provides evidence that
while using even somewhat high laser settings and oxygen flow rate, l
aser induced fires can be avoided. We conclude that use of the laser i
n the presence of oxygen is safe, provided the target area is free of
combustible fuels. Despite this assurance, laser mishaps are serious b
ecause they lead to both morbidity and mortality. It is our recommenda
tion that close attention be constantly paid to all details, thus redu
cing the hazard potential of laser energy on local factors in an oxyge
n-rich environment.