ENDOCRINE MUCIN-PRODUCING SWEAT GLAND CARCINOMA - A CUTANEOUS NEOPLASM ANALOGOUS TO SOLID PAPILLARY CARCINOMA OF BREAST

We describe two cases of a distinctive in situ and invasive cutaneous adnexal neoplasm occurring in the eyelid. Mucinous carcinoma represent ed the invasive portion of the tumor in one case, whereas the other in filtrated in small solid nests. The in situ component is identical to the recently described solid papillary carcinoma of the breast (endocr ine ductal carcinoma in situ). Both tumors produced intra-and extracel lular mucin, exhibited endocrine differentiation by immunohistochemist ry and ultrastructural analysis, and were positive for estrogen and pr ogesterone receptors.