The introduction of long-acting B-2-adrenoceptor agonists such as salm
eterol and formoterol has opened new perspectives for the treatment of
asthma and, also COPD, These drugs are particularly useful in bronchi
al asthma and meet the requirements of several treatment guidelines to
combine long-acting bronchodilator therapy with inhaled corticosteroi
ds in patients with persistent The role of long-acting B-2-adrenocepto
r agonists for management of COPD is less clear. While effects on lung
function will be small, parameters of improved quality of life and ex
ercise tolerance may verify the clinical role of long-acting beta(2)-a
drenoceptor agonists for COPD treatment in the future.