Aims: To investigate the prevalence of squamous epidermoid inclusion c
ysts after wide-core needle biopsy, Methods and results: Epidermoid in
clusion cysts were found in five of 17 surgical excisions (29%) after
preliminary wide-core needle biopsies in a 7-month period. Thereafter
they were not seen in 26 subsequent postwide-core surgical excisions i
n a period of 6 months, Conclusions: The cysts appear to be an iatroge
nic complication of wide-core biopsy and need morphological recognitio
n in order to avoid confusion with spontaneous squamous metaplasia of
benign or malignant breast epithelium. Longer term implications are un
known.