M. Vekemans et al., CONTINUATION RATES WITH A LEVONORGESTREL-RELEASING CONTRACEPTIVE IMPLANT (NORPLANT(R)) - A PROSPECTIVE-STUDY IN BELGIUM, Contraception, 56(5), 1997, pp. 291-299
Contraceptive protection offered by a method depends on its duration o
f use, which reflects costs, side effects, and relatives' opinions. Th
is study investigated in Norplant((R)) implants users the continuation
rates, some of their determinants, and the motives for removals. Sinc
e 1988, 612 Norplant implants sets, designed to protect for 5 years, h
ave been inserted. Observing 13,907 months of use, we determined over
time the continuation rates and how age, parity, circumstances at inse
rtion (postpartum, postabortum, others), and patronymic origins (surro
gate for sociocultural factors) influenced them. Statistics included K
aplan-Meier's method and log rank tests, and uni-and multivariate Cox
models. Continuation increased with age and depended on sociocultural
factors. Parity exerted influence only in younger women. Median durati
on of use was 3 years 11 months. Removals before 5 years related almos
t equally to irregular bleeding, other side effects, and pregnancy wis
h. The cumulative 5-year failure rate was 1.5%. Unsatisfied users retu
rned earlier, distorting the first results. A literature search showed
that implants yield, in the mean, slightly better continuation figure
s than do intrauterine devices, and clearly higher than those obtained
with pills and injectables. To optimize costs and counseling, warning
s about the risk of short duration of use in young nullipara, especial
ly if negative sociocultural influences prevail, are recommended. In n
o category are the implants absolutely to be avoided. Individual and p
rogrammatic contraceptive choice should take into account the expected
continuation of use. (C) 1997 Elsevier Science Inc. All rights reserv
ed.