THE SYNTHESIS OF DI(HYDROXYALKYL) SUBSTITUTED BICYCLIC GUANIDINES

Authors
MADDER A MUNSTER I ROLLE U DECLERCQ PJ
Citation
A. Madder et al., THE SYNTHESIS OF DI(HYDROXYALKYL) SUBSTITUTED BICYCLIC GUANIDINES, Bulletin des Societes chimiques belges, 106(9-10), 1997, pp. 613-621
Citations number
28
Categorie Soggetti
Chemistry
Journal title
Bulletin des Societes chimiques belges → ACNP
ISSN journal
00379646
Volume
106
Issue
9-10
Year of publication
1997
Pages
613 - 621
Database
ISI
SICI code
0037-9646(1997)106:9-10<613:TSODSB>2.0.ZU;2-1
Abstract
The synthesis of the enantiomerically pure bicyclic guanidines 3a and 3b is described. The convergent strategy is based on methodology devel oped by Schmidtchen. The therefore required amine components 6 and 9 a re obtained from methionine and L-glutamic acid, respectively.