The present study was designed to investigate choroidal perfusion in p
rimary open-angle glaucoma patients with statistically elevated (HPG)
and statistically normal (NPG) intraocular pressure (IOP) and in ocula
r hypertensive volunteers (OHT) before and after application of topica
l antiglaucomatous drugs. When compared to age-matched healthy control
s, ocular pulse amplitude (OPA) and IOP were significantly increased i
n OHT and unchanged in HPG; in NPG, the IOP was unchanged, and the OPA
was significantly reduced. The topical antiglaucomatous drugs used in
this study reduced IOP, but did not increase OPA. When compared to HP
G and NPG, OHT subjects showed increased choroidal perfusion which may
help to prevent glaucomatous optic nerve damage.