M. Inoue et al., IRIDOPATHY IN EYES WITH PROLIFERATIVE DIABETIC-RETINOPATHY - DETECTION OF EARLY-STAGE OF RUBEOSIS IRIDIS, Ophthalmologica, 212(1), 1998, pp. 15-18
Forty-two eyes of 31 proliferative diabetic retinopathy patients with
laser flare intensity greater than or equal to 20 photon counts/ms und
erwent fluorescein iris angiography to evaluate any changes in the blo
od-iris barrier and iris biomicroscopy to detect rubeosis iridis. Fluo
rescein iris angiography revealed abnormal dye leakage in all eyes. La
ser flare intensity significantly correlated with the degree of dye le
akage. Eyes with dye leakage from only the pupillary border]lad no rub
eosis. In 11 out of 18 (61%,) eyes with moderate dye leakage, prolifer
ative diabetic iridopathy with early rubeosis was present in 8 and adv
anced iridopathy in 3 eyes. In all eyes with excessive leakage, rubeos
is iridis was detected under slitlamp examination, High laser flare in
tensity has a close relationship with advanced blood-ocular barrier di
sruption, High flare intensity may be a helpful indicator in detecting
incipient rubeosis or advanced diabetic iridopathy.