A. Turbahn et al., DOSE-RESPONSE STUDY OF ENROFLOXACIN AGAINST RIEMERELLA ANATIPESTIFER SEPTICEMIA IN MUSCOVY AND PEKIN DUCKLINGS, Avian pathology, 26(4), 1997, pp. 791-802
The efficacy of enrofloxacin against Riemerella anatipestifer (formerl
y Pasteurella anatipestifer) septicaemia of Muscovy and Pekin duckling
s was assessed in an artificial challenge model which reproduced typic
al duck riemerellosis with very high mortality. Mortality, clinical si
gns, gross lesions, microbiological clearance, feed intake and body we
ight gain were the efficacy criteria studied. A pulsing medication in
drinking water for 4 h at 25, 50 or 100 ppm enrofloxacin on the first
day, followed by 12.5, 25 or 50 ppm, respectively, on the following 4
days, provided clinical cure of R. anatipestifer septicaemia at all do
sages tested. An optimum dosage of 50 ppm enrofloxacin, followed by 25
ppm was established.