Background Pancreatic pseudocysts may produce pain, or biliary or duod
enal obstruction. Those over 6 cm in diameter or associated with chron
ic pancreatitis are unlikely to resolve and usually require interventi
on. There are a number of treatment modalities available and this pape
r reviews the role of endoscopic drainage. Methods AU articles and cas
e reports quoted on Medline (National Library of Medicine, Washington
DC, USA) containing the text words 'endoscopy' and 'pseudocyst', and c
itations from these references mere reviewed. Results Endoscopic drain
age is technically feasible in around 50 per cent of pancreatic pseudo
cysts associated with chronic pancreatitis. Successful drainage occurr
ed in 82-89 per cent, The major complication is bleeding which require
d surgery for control in 5 per cent of procedures. One death attributa
ble to the procedure has been reported, Recurrence rates range from 6
to 18 per cent with up to 4 years' follow-up. As in open surgery, recu
rrence is highest with drainage via the stomach. Conclusion Endoscopic
drainage provides a minimally invasive approach to pseudocyst managem
ent, with success and recurrence rates similar to those of open surger
y but with lower morbidity and mortality rates, It should be considere
d the treatment of choice for pseudocysts less than 1 cm thick which b
ulge into the stomach or duodenum, or for those which communicate with
the main pancreatic duel.