R. Ouseph et al., PATENT FORAMEN OVALE PRESENTING AS REFRACTORY HYPOXEMIA AFTER HEART-TRANSPLANTATION, Journal of the American Society of Echocardiography, 10(9), 1997, pp. 973-976
Hypoxemia can be an early life-threatening complication of orthotopic
heart transplantation. Commonly, hypoxemia after orthotopic heart tran
splantation is due to pulmonary hypertension or pulmonary complication
s. Rarely, structural defects either in the donor or recipient heart c
an lead to life-threatening hypoxemia. This case illustrates hypoxemia
after orthotopic heart transplantation caused by the development of a
right-to-left shunt through a patent foramen ovale in the recipient w
hich had preoperatively been hemodynamically insignificant. The refrac
tory hypoxemia required emergency surgical correction of the patent fo
ramen ovale within the first postoperative week. In addition, this cas
e illustrates the unique application of different methods of echocardi
ograms providing noninvasive diagnosis of structural defects in orthot
opic heart transplantation.