The neuroanatomic proximity of the larynx to the hypopharynx and proxi
mal esophagus make it particularly vulnerable to diseases that occur i
n those 2 areas. This is particularly true of gastroesophageal reflux
disease (GERD), There is increasing awareness of this relationship, an
d dysphonias from gastroesophageal reflux (GER) are far more common th
an previously realized. The symptoms and findings of reflux laryngitis
, vocal nodules, Reinke's edema, contact ulcer and granuloma, laryngea
l stenosis, and paroxysmal laryngospasm are presented, and diagnostic
protocols for each disorder are suggested. The treatment varies with t
he severity of each problem. Conservative lifestyles and dietary contr
ol are helpful, but long-term medical therapy with HPI Hr, and prokine
tic drugs are usually needed. Surgical therapy may be indicated for su
ch life-threatening problems as laryngeal stenosis and paroxysmal lary
ngospasm. The need for physician and patient awareness, research, and
improved and less expensive therapy are discussed. (C) 1997 by Excerpt
a Medica, Inc.