SYNTHESIS OF A SERINAMIDE BY AMINOLYSIS OF AN N-UNSUBSTITUTED ALPHA-AMINO ESTER

Authors
REID JG CHEN BC NJEGOVAN JF QUINLAN SL STARK DR
Citation
Jg. Reid et al., SYNTHESIS OF A SERINAMIDE BY AMINOLYSIS OF AN N-UNSUBSTITUTED ALPHA-AMINO ESTER, Organic process research & development, 1(2), 1997, pp. 174-175
Citations number
20
Journal title
Organic process research & development → ACNP
ISSN journal
10836160
Volume
1
Issue
2
Year of publication
1997
Pages
174 - 175
Database
ISI
SICI code
1083-6160(1997)1:2<174:SOASBA>2.0.ZU;2-8
Abstract
L-2-Amino-3-hydroxy-N-pentylpropanamide (1) was readily prepared and i solated as its oxalate salt in 81% yield and >99% eethrough a ''one-po t'' process from L-serine methyl ester (4).