Background: Photorefraktive keratectomy (PRK) is the most frequent ref
ractive surgical procedure worldwide. The central corneal thickness is
reduced due to removal of the anterior stroma, including Bowman's lay
er, with a laser beam. This procedure results in considerable alterati
ons of the corneal structure. What does this mean for the mechanical p
roperties of the cornea? Methods: lntraocular pressure was increased v
ia a 180 degrees tilt. Before and during this procedure, corneal topog
raphy was measured by photokeratoscopy. We examined 26 patients after
PRK and 25 controls who had not undergone any surgical procedure. Resu
lts: The corneal center flattened by 0.038 +/- 0.05 dpt (P > 0.05) in
the PRK patients and by 0.187 +/- 0.045 dpt (P < 0.05) in the control
group. PRK patients within 1 year after operation showed a minimal cen
tral corneal steepening,whereas PRK patients after more than 1 year sh
owed a reaction similar to that in normal corneas (P < 0.05). Conclusi
on: Corneal stability is altered after PRK. After 1 year corneal stabi
lity seems to normalize due to stromal remodelling.