Ka. Kuhlman et Wj. Hennessey, SENSITIVITY AND SPECIFICITY OF CARPAL-TUNNEL SYNDROME SIGNS, American journal of physical medicine & rehabilitation, 76(6), 1997, pp. 451-457
The sensitivity and specificity of six carpal tunnel syndrome (CTS) si
gns were determined by evaluating 143 subjects (228 hands) with sympto
ms of CTS. Immediately after performing the six physical examination t
ests, standard nerve conduction studies were performed on all 228 hand
s to determine the presence or absence of CTS. CTS was present in 142
hands and absent in 86 hands. The signs were not very sensitive (23-69
%), but were fairly specific (66-87%) for CTS. A square-shaped wrist a
nd abductor pollicis brevis weakness were the most sensitive signs (69
and 66%, respectively), and are recommended as part of the examinatio
n of CTS. Median nerve hypesthesia and the Phalen sign both have fair
sensitivity (51%) but good specificity (85 and 76%, respectively). The
median nerve compression sign and the Hoffmann-Tinel sign both have p
oor sensitivity (28 and 23%, respectively), and thus are less helpful
in evaluating subjects with suspected CTS.