M. Malmqvist et R. Karlsson, BIOMOLECULAR INTERACTION ANALYSIS - AFFINITY BIOSENSOR TECHNOLOGIES FOR FUNCTIONAL-ANALYSIS OF PROTEINS, CURRENT OPINION IN CHEMICAL BIOLOGY, 1(3), 1997, pp. 378-383
The introdution of affinity-based biosensors has permitted label-free
functional analysis of biomolecular interactions in real time. A varie
ty of methods are now based on BIOCORE(registered trade-mark) and IAsy
s technology and have mainly been used to determine kinetics and affin
ity constants.