MASS-SPECTROMETRY AT LOW AND HIGH-MASS

The introduction of novel methods as well as expanding applications to diverse areas highlight truly impressive progress in mass spectrometr y. These developments are illustrated here by two seemingly different areas of research: new methods designed for the determination of isoto pic enrichment and novel ionization methods; and mass analyzers which have enabled the precise determination of the molecular weight of prot eins and large oligonucleotides.