DISTRIBUTION OF HLA-DQA1 ALLELES IN ARAB AND PAKISTANI INDIVIDUALS FROM DUBAI, UNITED-ARAB-EMIRATES

Authors
TAHIR MA ALKHAYAT AQ ALSHAMALI F BUDOWLE B NOVICK GE
Citation
Ma. Tahir et al., DISTRIBUTION OF HLA-DQA1 ALLELES IN ARAB AND PAKISTANI INDIVIDUALS FROM DUBAI, UNITED-ARAB-EMIRATES, Forensic science international, 85(3), 1997, pp. 219-223
Citations number
18
Categorie Soggetti
Medicine, Legal
Journal title
Forensic science international → ACNP
ISSN journal
03790738
Volume
85
Issue
3
Year of publication
1997
Pages
219 - 223
Database
ISI
SICI code
0379-0738(1997)85:3<219:DOHAIA>2.0.ZU;2-A
Abstract
PCR-based typing of the HLA-DQA1 locus, using allele specific oligonuc leotide (ASO) probes and reverse dot blot methodology was used to dete rmine allelic distributions and construct a database for Arab and Paki stani individuals living in Dubai. Genotype and allelic frequencies we re calculated, and the data were tested for departures from Hardy-Wein berg (HWE) equilibrium. The most frequent HLA-DQA1 alleles among Dubai an Arabs are DQA1 4 and 1.2. Among Pakistanis, the most frequent allel e is also DQA1 4. No significant deviations from HWE were detected. (C ) 1997 Elsevier Science Ireland Ltd.