INDUSTRIAL-SCALE SYNTHESIS OF THIOPHOSGENE AND ITS DERIVATIVES

Authors
GRAYSON JI
Citation
Ji. Grayson, INDUSTRIAL-SCALE SYNTHESIS OF THIOPHOSGENE AND ITS DERIVATIVES, Organic process research & development, 1(3), 1997, pp. 240-246
Citations number
43
Journal title
Organic process research & development → ACNP
ISSN journal
10836160
Volume
1
Issue
3
Year of publication
1997
Pages
240 - 246
Database
ISI
SICI code
1083-6160(1997)1:3<240:ISOTAI>2.0.ZU;2-E
Abstract
Thiophosgene is manufactured on a mulittonne scale, using the continuo us chlorination of carbon disulfide under aqueous conditions to prepar e the key intermediate perchloromethyl mercaptan, The development of t his process is described, and the uses of thiophosgene in the manufact ure of chlorothioformates and isothiocyanates are reviewed.