THE MARSHALL-SYNDROME - REPORT OF A NEW FAMILY AND REVIEW OF THE LITERATURE

The Marshall syndrome is an autosomal dominant trait comprising ocular abnormalities, sensorineural hearing loss, craniofacial anomalies, an d anhidrotic ectodermal dysplasia, To our knowledge, only seven additi onal multigenerational families have been reported since the initial d escription of the disorder by Marshall in 1958. We present a family in which six members in four generations are affected with apparent Mars hall syndrome. We also review and compare similar disorders, such as S tickler, Weissenbacher-Zweimuller, and Wagner syndromes, and conclude that Marshall syndrome is a distinct entity. (C) 1997 Wiley-Liss, Inc.