CASCADE AND SEQUENTIAL PALLADIUM-CATALYZED CYCLIZATION-AZIDE CAPTURE-1,3-DIPOLAR CYCLOADDITION ROUTE TO COMPLEX TRIAZOLES

Authors
GARDINER M GRIGG R SRIDHARAN V VICKER N
Citation
M. Gardiner et al., CASCADE AND SEQUENTIAL PALLADIUM-CATALYZED CYCLIZATION-AZIDE CAPTURE-1,3-DIPOLAR CYCLOADDITION ROUTE TO COMPLEX TRIAZOLES, Tetrahedron letters, 39(5-6), 1998, pp. 435-438
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
5-6
Year of publication
1998
Pages
435 - 438
Database
ISI
SICI code
0040-4039(1998)39:5-6<435:CASPCC>2.0.ZU;2-T
Abstract
Palladium catalysed processes involving sequential cyclisation of aryl iodides onto proximate allenes with capture by NaN3 (and NaO2SPh) fol lowed by a 1,3-dipolar cycloaddition reaction utilizing DMAD, methyl p ropiolate and norbomadiene are described. When utilising the latter, t he sequence can be carried out as a one-pot protocol which terminates with a retro Diels-Alder reaction. (C) 1997 Elsevier Science Ltd. All rights reserved.