CYCLOADDITIONS OF AROMATIC IMINES TO ENANTIOMERICALLY PURE STABILIZEDAZOMETHINE YLIDS - CONSTRUCTION OF THREO (2S,3R)-3-ARYL-2,3-DIAMINO ACIDS

Authors
ALKER D HARWOOD LM WILLIAMS CE
Citation
D. Alker et al., CYCLOADDITIONS OF AROMATIC IMINES TO ENANTIOMERICALLY PURE STABILIZEDAZOMETHINE YLIDS - CONSTRUCTION OF THREO (2S,3R)-3-ARYL-2,3-DIAMINO ACIDS, Tetrahedron letters, 39(5-6), 1998, pp. 475-478
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
5-6
Year of publication
1998
Pages
475 - 478
Database
ISI
SICI code
0040-4039(1998)39:5-6<475:COAITE>2.0.ZU;2-S
Abstract
Chiral stabilized azomethine ylids derived from reaction of (5S)-pheny lmorpholin-2-one (1) with aromatic imines undergo efficient and highly diastereocontrolled cycloaddition with a second molecule of imine to furnish products which may be converted into enantiomerically pure thr eo (2S, 3R)-3-aryl-2,3-diamino acids. (C) 1997 Elsevier Science Ltd. A ll rights reserved.