RING-OPENING OF CHIRAL N-(3,4-DIHYDRO-4-OXOQUINAZOLIN-3-YL)-SUBSTITUTED AZIRIDINES (Q-ASTERISK-SUBSTITUTED AZIRIDINES) - ACCESS TO Q-ASTERISK-FREE CHIRONS

Authors
ATKINSON RS AYSCOUGH AP GATTRELL WT RAYNHAM TM
Citation
Rs. Atkinson et al., RING-OPENING OF CHIRAL N-(3,4-DIHYDRO-4-OXOQUINAZOLIN-3-YL)-SUBSTITUTED AZIRIDINES (Q-ASTERISK-SUBSTITUTED AZIRIDINES) - ACCESS TO Q-ASTERISK-FREE CHIRONS, Tetrahedron letters, 39(5-6), 1998, pp. 497-500
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
5-6
Year of publication
1998
Pages
497 - 500
Database
ISI
SICI code
0040-4039(1998)39:5-6<497:ROCN>2.0.ZU;2-M
Abstract
The presence of the quinazolin-4(3H)-one ring (Q) in N-(Q*)-aziridine s facilitates ring-opening by nucleophiles: removal of the Q group fr om enantiopure ring-opened products gives useful chirons. (C) 1997 Els evier Science Ltd. All rights reserved.