We compared the performance of precordial QT dispersion, late potentia
ls on the signal-averaged electrocardiogram (EGG), and reduced left ve
ntricular ejection fraction for identification of inducible ventricula
r tachycardia (VT) in 162 patients undergoing electrophysiologic study
(EPS). QT(apex) dispersion in 56 patients with inducible VT (72 +/- 5
5 msec) was greater than that in 106 patients without inducible VT (55
+/- 36 msec, p < 0.01); dispersion was greater in both groups than in
144 normal subjects (33 +/- 19 msec), A QT(apex) dispersion partition
of more than 68 msec, the upper ninety-fifth percentile in normal sub
jects, identified inducible VT with a specificity of 75% and a sensiti
vity of 45%. Although the performances of late potentials (specificity
82%, sensitivity 59%) and reduced election fraction (specificity 86%,
sensitivity 54%) were each stronger than QT dispersion alone for iden
tification of inducible VT, abnormal QT(apex), dispersion remained a s
ignificant additional predictor of inducible VT in a logistic regressi
on model that included the three variables (specificity 78%, sensitivi
ty 75%).