ENANTIOSPECIFIC TOTAL SYNTHESIS OF A NOVEL ARACHIDONIC-ACID METABOLITE 3-HYDROXYEICOSATETRAENOIC ACID

Authors
BHATT RK FALCK JR NIGAM S
Citation
Rk. Bhatt et al., ENANTIOSPECIFIC TOTAL SYNTHESIS OF A NOVEL ARACHIDONIC-ACID METABOLITE 3-HYDROXYEICOSATETRAENOIC ACID, Tetrahedron letters, 39(3-4), 1998, pp. 249-252
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
3-4
Year of publication
1998
Pages
249 - 252
Database
ISI
SICI code
0040-4039(1998)39:3-4<249:ETSOAN>2.0.ZU;2-F
Abstract
The enantiomers R- and S-3-hydroxyeicosatetraenoic acid 11a, 11b were synthesized from coupling of a chiral aldehyde 7 with a Wittig salt 4, which were derived from 2-deoxy-D-ribose and arachidonic acid, respec tively. (C) 1997 Elsevier Science Ltd. All rights reserved.