A NOVEL FUNCTION-BASED ON A LINEAR ARRANG EMENT OF CROWN-ETHERS ALONGTHE ALPHA-HELIX ROD

Authors
HIROTA Y NAKANISHI F KINOSHITA T TSUJITA Y YOSHIMIZU H
Citation
Y. Hirota et al., A NOVEL FUNCTION-BASED ON A LINEAR ARRANG EMENT OF CROWN-ETHERS ALONGTHE ALPHA-HELIX ROD, Kobunshi ronbunshu, 54(12), 1997, pp. 966-973
Citations number
31
Journal title
Kobunshi ronbunshu → ACNP
ISSN journal
03862186
Volume
54
Issue
12
Year of publication
1997
Pages
966 - 973
Database
ISI
SICI code
0386-2186(1997)54:12<966:ANFOAL>2.0.ZU;2-V
Abstract
In order to construct a navel functional polymer, we prepared the alph a-helical polypeptide with parallel arrangement of benzo-18-crown ethe r side chains (seq-MG/18CrG) by using the ''monolayer reaction method' '. Interaction between seq-MG/18CrG and cation was characterized bg sp ectrofluometric and picrate extraction methods to evaluate their stabi lity (K) and stoichiometry (n) constants, It was found, as a result, t hat seq-MG/18CrG interacted with cesium ion to form 2(benzo-crown) : 1 (cesium ion) complex species and the stability constant was much large r than that of random copolypeptide-cesium complex. This study found t hat this supramolecular crown ether acts as an unique ionophore for ce sium ion.