D. Schmidt et al., VISUAL RECOVERY AFTER ACUTE CHOROIDAL ISCHEMIA WITH PARTIAL RETINAL HYPOPERFUSION, DEMONSTRATED BY FLUORESCEIN ANGIOGRAPHY, Neuro-ophthalmology, 18(4), 1997, pp. 205-213
Background: Compared with retinal vascular disease, choroidal ischemia
has received little attention. Patients: The case histories of three
patients are described. During embolization, a 32-year-old man complai
ned of sudden deterioration in vision. An 82-year-old man with arteria
l hypertension, diabetes mellitus, and hyperlipoproteinemia reported a
complete unilateral visual loss. A 72-year-old man (cigarette smoker)
with arterial hypertension, diabetes mellitus, and a high-degree inte
rnal carotid artery stenosis developed a headache accompanied by sudde
n unilateral loss of vision. Results: The three patients showed ischem
ic signs predominantly in the choroid, but also subtle signs in the re
tina (patient 2) and branch retinal artery occlusion (patient 3). On o
phthalmoscopy alone, no clear-cut choroidal hypoperfusion was detected
in two patients. However, diagnosis of choroidal hypoperfusion was es
sentially made by fluorescein angiography. The choroidal hypoperfusion
almost completely surrounded the optic disk in two patients. Normal v
ision returned spontaneously in one patient, in spite of an almost com
plete temporal choroidal ischemia. In patient 2, a partial recovery fo
llowed treatment of his arterial hypertension. Patient 3 also showed a
good visual recovery after treatment with heparin, massage of the glo
be, and antihypertensive drugs. The circulation time of the choroidal
angiographic filling defects was Io sec and longer, but it became much
shorter after several weeks. Conclusion: Visual recovery was good in
all patients despite ischemic signs in the choroid. No scarring of the
central retinal pigment epithelium was observed.