J. Rutishauser et Er. Froesch, SIGNAL PEPTIDE AND NEUROPHYSIN-II GENE-MUTATIONS IN HEREDITARY CENTRAL DIABETES-INSIPIDUS, News in physiological sciences, 12, 1997, pp. 67-71
Recent studies on the molecular background of central diabetes insipid
us have identified several mutations in the gene encoding antidiuretic
hormone and its carrier protein neurophysin II. This article discusse
s the impact of such mutations on precursor processing and transport i
n neuronal cells.