Ja. Bofill et al., NULLIPAROUS ACTIVE LABOR, EPIDURAL ANALGESIA, AND CESAREAN DELIVERY FOR DYSTOCIA, American journal of obstetrics and gynecology, 177(6), 1997, pp. 1465-1470
OBJECTIVE: Our purpose was to examine the effect of epidural analgesia
on dystocia-related cesarean delivery in actively laboring nulliparou
s women. STUDY DESIGN: Active labor was confirmed in nulliparous women
by uterine contractions, cervical dilatation of 4 cm, effacement of 8
0%, and fetopelvic engagement. Patients were randomized to one of two
groups: epidural analgesia or narcotics. A strict protocol for labor m
anagement was in place. Patients recorded the level of pain at randomi
zation and at hourly intervals on a visual analog scale. Elective outl
et operative vaginal delivery was permitted. RESULTS: One hundred wome
n were randomized. No difference in the rate of cesarean delivery for
dystocia was noted between the groups (epidural 8%, narcotic 6%; p = 0
.71). No significant differences were noted in the lengths of the firs
t (p = 0.54) or second (p = 0.55) stages of labor or in any other time
variable. Women with epidural analgesia underwent operative vaginal d
elivery more frequently (p = 0.004). Pain scores were equivalent at ra
ndomization, but large differences existed at each hour thereafter. Th
e number of patients randomized did not achieve prestudy estimates. A
planned interim analysis of the results demonstrated that we were unli
kely to find a statistically significant difference in cesarean delive
ry rates in a trial of reasonable duration. CONCLUSIONS: With strict c
riteria for the diagnosis of labor and with use of a rigid protocol fo
r labor management, there was no increase in dystocia-related cesarean
delivery with epidural analgesia.