ANALYSIS OF THE TYROSINE-HYDROXYLASE AND DOPAMINE D4 RECEPTOR GENES IN A CROATIAN SAMPLE OF BIPOLAR-I AND UNIPOLAR PATIENTS

Authors
ORUC L VERHEYEN GR FURAC I JAKOVLJEVIC M IVEZIC S RAEYMAEKERS P VANBROECKHOVEN C
Citation
L. Oruc et al., ANALYSIS OF THE TYROSINE-HYDROXYLASE AND DOPAMINE D4 RECEPTOR GENES IN A CROATIAN SAMPLE OF BIPOLAR-I AND UNIPOLAR PATIENTS, American journal of medical genetics, 74(2), 1997, pp. 176-178
Citations number
28
Categorie Soggetti
Genetics & Heredity
Journal title
American journal of medical genetics → ACNP
ISSN journal
01487299
Volume
74
Issue
2
Year of publication
1997
Pages
176 - 178
Database
ISI
SICI code
0148-7299(1997)74:2<176:AOTTAD>2.0.ZU;2-M
Abstract
We selected 83 patients with bipolar disorder type I or unipolar recur rent major depression and 71 healthy controls for genetic analysis of the tyrosine hydroxylase and the dopamine D4 receptor gene, No signifi cant association was found between bipolar disorder type I and unipola r recurrent major depression and the polymorphisms located near these genes. Therefore, the hypothesis that the tyrosine hydroxylase and the dopamine D4 receptor genes may be involved in the etiology of bipolar disorder and unipolar recurrent major depression is not supported in our study. (C) 1997 Wiley-Liss, Inc.