DIFFERENCES IN THE DYNAMICS OF OXIDIZED AND REDUCED CYTOCHROME-C MEASURED BY MOSSBAUER-SPECTROSCOPY

Authors
FROLOV EN GVOSDEV R GOLDANSKII VI PARAK FG
Citation
En. Frolov et al., DIFFERENCES IN THE DYNAMICS OF OXIDIZED AND REDUCED CYTOCHROME-C MEASURED BY MOSSBAUER-SPECTROSCOPY, JBIC. Journal of biological inorganic chemistry, 2(6), 1997, pp. 710-713
Citations number
18
Journal title
JBIC. Journal of biological inorganic chemistry → ACNP
ISSN journal
09498257
Volume
2
Issue
6
Year of publication
1997
Pages
710 - 713
Database
ISI
SICI code
0949-8257(1997)2:6<710:DITDOO>2.0.ZU;2-Z
Abstract
The temperature dependence of the mean square displacement of the iron atom in reduced and oxidized cytochrome c has been studied by Mossbau er spectroscopy. The flexibility of the protein, labeled by the modes coupling to the iron, is diminished upon reduction. The differences in flexibility are sufficient to explain the differences in physicochemi cal properties between the oxidized and the reduced forms.