Background. Mortality from ischaemic heart disease (IHD) and prevalenc
e of coronary arteriosclerosis are low in Inuit of Greenland (Greenlan
ders). Aetiological considerations have so far focused mostly on diet
and blood lipids, The present study is a comprehensive analysis of beh
avioural, clinical and serological cardiovascular risk factors for IHD
in Greenlanders. Methods. An interview survey from West Greenland (n
= 1436) was supplemented with clinical measurements and blood sampling
in selected towns and villages (n = 264). Results. The average consum
ption of marine mammals and fish was 28 meals per month. In Greenland
14% of males and 30% of females were physically inactive compared with
14% and 17% in the general population of Denmark; 79% were current sm
okers and 22% smoked 15+ cigarettes per day compared with 42% and 21%
in Denmark. High density lipoprotein (HDL) concentration was 1.6 mmol/
l in Greenland (1.1 in Denmark) and triglyceride concentration 1.0 mmo
l/l (1.5). Obesity, blood pressure and total cholesterol were similar
in Greenland and Denmark. There were significant differences between G
reenlanders with a predominantly traditional childhood and those with
a more westernized childhood with regard to diet, physical activity (i
n women) and blood lipids. Conclusions. In spite of an increased weste
rnization of the Greenlanders' lifestyle and a high prevalence of seve
ral cardiovascular risk factors, mortality from IHD is still low. The
change in risk factor patterns is, however, recent and an increased IH
D mortality is still to be expected. Preventive measures should be ini
tiated to reduce risk factors but they must take into consideration po
ssible negative consequences of e.g. traditional outdoor activities an
d the consumption of marine mammals.