NITRITE-SELECTIVE AND CHLORIDE-SELECTIVE FLUORESCENT NANO-OPTODES ANDIN IN-VITRO APPLICATION TO RAT CONCEPTUSES

Nitrite- and chloride-selective, ion correlation-based, nano-optodes h ave been prepared for application in vitro. These fluorescent, liquid polymer based sensors have theoretically predictable responses to anio n activities and good selectivity, The nitrite sensor, prepared with a vitamin B-12 derivative ionophore, would be useful for determination of oxidized nitric oxide, Chloride nano-optodes, as well as micro-opto des, prepared with an indium porphyrin ionophore, were utilized to det ermine chloride levels both on the surface and inside the visceral yol k sac of organogenesis-stage rat conceptuses.