Ej. Calabrese et al., SOIL INGESTION ESTIMATES FOR CHILDREN RESIDING ON A SUPERFUND SITE, Ecotoxicology and environmental safety, 36(3), 1997, pp. 258-268
Soil ingestion estimates were obtained from a stratified, simple rando
m sample of 64 children aged 1-4 years residing on a superfund site in
Montana. The study was conducted during the month of September for 7
consecutive days. The study utilized a mass-balance methodology in whi
ch eight naturally occurring soil tracers (Al, Si, Ti, Ce, Nd, La, Y,
and Zr) believed to be poorly absorbed by the gastrointestinal tract w
ere employed to provide soil ingestion estimates. Food and fecal sampl
es were analyzed on a daily basis. Soil/dust samples representative of
where the children played during the study period were obtained. Very
high compliance among the participants was maintained throughout the
study. The identical methodology employed in the childrens' study was
used in an adult study of tracer recovery in 10 subjects over 28 days
of observation to provide validation that soil ingestion over the rang
e of 20 to 500 mg/day could be detected. Soil ingestion was estimated
by each soil tracer via traditional methods as well as by an improved
approach using five trace elements (Al, Si, Ti, Y, and Zr), called the
Best Tracer Method (BTM), which substantially corrects for error due
to misalignment of tracer input and output as well as error occurring
from ingestion of tracers from nonfood, nonsoil sources, while being i
nsensitive to the particle size of the soil/dust ingested. According t
o the BTM, the median soil ingestion was less than 1 mg/day while the
upper 95% was 160 mg/day. No significant age (1 year vs 2, vs 3) or se
x-related differences in soil ingestion were observed. These estimates
are lower than estimates observed in another study in Massachusetts d
uring September and October. Significant methodological improvements i
n this study as compared to previously conducted soil ingestion studie
s include the selection of a representative sample of children, longer
study duration, inclusion of dietary recommendations to reduce food t
racer input and variability, use of the BTM, and a stronger adult vali
dation study with respect to number of subjects, and duration and rang
e of possible soil ingestion rates. Despite these methodological impro
vements, evidence exists that this study displays a net residual negat
ive error, suggesting that the above estimates are below the true soil
ingestion. The magnitude of this residual negative error cannot be qu
antified with the BTM but is likely to not affect the median by more t
han 40 mg/day, while the impact of such an error on the upper end of t
he distribution is more uncertain. (C) 1997 Academic Press.