RADIATION-DOSIMETRY FOR INDIUM-111-PENTETREOTIDE

We present radiation dose estimates for In-111-pentetreotide, Methods: Kinetic data were gathered in 10 subjects at two different sites. A c ompartmental model was used to fit the data, including retention, in t hree major organs and excretion. Results: The data were consistent for the subjects at both sites. The organ receiving the highest dose was the kidneys (0.52 mGy/MBq); the effective dose equivalent was 0.1 mSv/ MBq, and the effective dose was 0.073 mSv/MBq. Conclusion: The results of this study provide the basis for evaluation of radiation safety of this drug.