Eb. Nelson et al., ATTENTIONAL PERFORMANCE IN PATIENTS WITH PSYCHOTIC AND NONPSYCHOTIC MAJOR DEPRESSION AND SCHIZOPHRENIA, The American journal of psychiatry, 155(1), 1998, pp. 137-139
Objective: The authors examined Continuous Performance Test scores of
patients with major depression with or without psychosis and schizophr
enia. Method: Patients with major depression with psychosis (N=13), ma
jor depression without psychosis (N=14), and schizophrenia (N=15) and
normal volunteers (N=14) completed the degraded-stimulus version of th
e Continuous Performance Test. Patients were rated with the Hamilton D
epression Rating Scale and measures of positive formal thought disorde
r. Results. Continuous Performance Test scores of patients with major
depression with psychosis and schizophrenia were significantly worse t
han those of patients with major depression without psychosis and of n
ormal volunteers. Positive formal thought disorder was correlated with
performance on this test in patients with schizophrenia. Conclusions:
These findings suggest that attentional impairment on the Continuous
Performance Test is associated with psychosis in general and may be sp
ecifically associated with positive formal thought disorder in patient
s with schizophrenia.