ELECTROCHEMICAL DETECTION OF DISODIUM 3,3'-AZOBIS-(6-HYDROXY-)BENZOATE (OLSALAZINE SODIUM)

Authors
ERIKSSON A NYHOLM L
Citation
A. Eriksson et L. Nyholm, ELECTROCHEMICAL DETECTION OF DISODIUM 3,3'-AZOBIS-(6-HYDROXY-)BENZOATE (OLSALAZINE SODIUM), Electroanalysis, 9(16), 1997, pp. 1291-1293
Citations number
4
Journal title
Electroanalysis → ACNP
ISSN journal
10400397
Volume
9
Issue
16
Year of publication
1997
Pages
1291 - 1293
Database
ISI
SICI code
1040-0397(1997)9:16<1291:EDOD3>2.0.ZU;2-G
Abstract
Electrochemical detection of disodium 3,3'-azobis-(6-hydroxy-)benzoate , olsalazine sodium, in reversed phase Liquid chromatography is shown to provide a detection limit of 40 fmol and a linear range extending u p to 4 nmol for an injection volume of 20 mu L. The method has been us ed for the determination of the solubility of olsalazine sodium in aqu eous solutions. The solubility was found to be 2 x 10(-8) M and 4 x 10 (-6) M at pH 1.0 and 3.5, respectively.