A. Bacskulin et al., AN ADJUVANT AFTERLOADING BRACHYTHERAPY DEVICE FOR USE AFTER ORBITAL EXENTERATION IN PATIENTS WITH ORBITAL MALIGNANCIES, German journal of ophthalmology, 5(6), 1997, pp. 484-488
In cases of malignant diseases situated within the orbit and threaten
to extend beyond it, removal of the orbit and periorbital contents may
be indicated followed by adjuvant chemotherapy or irradiation, An eff
ective radiotherapy device for treatment of residual or suspicious can
cer in the enucleated orbit consists of an external-beam radiation sou
rce (Co-60) and an intraoperatively fitted mould as a guide for the fl
exible afterloading tubes using a Ir source, Considering the physical
dose distribution and the local situation, this therapy permits a high
dose with homogeneous dose distribution to the target area of the orb
it but also allows significant dose reduction to adjunctive critical s
tructures. Four patients with different orbital malignancies were trea
ted by means of a combination of percutaneous radiotherapy with afterl
oading brachytherapy following orbital exenteration. The individual mo
uld of the orbital cavity is modeled at the end of the operation. The
technique of radiotherapy, dose distribution, and follow-up of the dis
ease are demonstrated. Orbital malignancies with an extremely poor pro
gnosis may profit from the application of this combined radiotherapy t
o avoid supraradical surgical intervention.