MICRO-STENT-I, INITIAL RESULTS, AND 6 MONTHS FOLLOW-UP BY QUANTITATIVE CORONARY ANGIOGRAPHY

The Micro stent(TM) (MS) is a balloon expandable stent that allows the treatment of stenoses in distal and tortuous coronary arteries. This prospective study was performed to evaluate initial and late results o f MS implantations. A total of 127 MS (101 in native coronary arteries and 26 in saphenous vein grafts) were implanted in 85 patients (1.5 s tents/pt, 65 male, and 20 female, age 62, +/-10 yr) with angina pector is class II-III: 21 (25%), angina pectoris class IV: 41 (48%), and acu te myocardial infarction: 23 (27%). Indications per segment treated (n =93): elective: 49 (53%); suboptimal balloon angioplasty (PTCA) result : 33 (35%); bailout: 11 (12%). The patients were discharged with 100 m g of aspirin daily unless other indications for oral anticoagulants we re present. Procedural success (diameter stenosis of 30% without the o ccurrence of clinical events within 3 wk) was 85%. Early clinical even ts (<3 wk included: death: 1%; subacute closure: 5%; coronary artery b ypass surgery (CABG): 1%; Vascular complications: 4%. Late clinical ev ents (3 wk-6 mo) included: acute myocardial infarction: 3%, PTCA 5%, C ABG 3%, angina class III-IV: 4%. Quantitative angiographic results wer e: the minimum lumen diameter increased from 0.90 +/- 0.72 before to 3 .05 +/- 0.48 mm (<P0.001) after stent implantation. At follow-up, whic h was 5.5 mo +/- 1.1 mo, 61/79 pts (77%), the loss in diameter was 0.9 0 +/- 0.68 mm. The net gain was 1.26 +/- 0.90 mm. The restenosis rate (diameter stenosis > 50% at FU) was 13%. This study demonstrates high procedural and late success rates of Micro stent implantations. (C) 19 98 Wiley-Liss, Inc.