Mj. Landray et Mj. Kendall, BETA-BLOCKERS IN HEART-FAILURE - A CARDIOPROTECTIVE THERAPY, Journal of clinical pharmacy and therapeutics, 22(3), 1997, pp. 181-185
Heart failure remains a major cause of morbidity and mortality despite
optimum treatment angiotensin-converting enzyme inhibitors diuretics.
Meta-analysis of recent placebo-controlled, randomized trials suggest
that treatment with beta-blockers may significantly reduce mortality
by 35%.